GMP Synthase 抗体 (Middle Region)
Quick Overview for GMP Synthase 抗体 (Middle Region) (ABIN2783438)
抗原
See all GMP Synthase (GMPS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- VCTALLNRAL NQEQVIAVHI DNGFMRKRES QSVEEALKKL GIQVKVINAA
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against GMPS. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human GMPS
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 693 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))
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别名
- GMPS
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背景
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In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
Alias Symbols: -
Protein Interaction Partner: UBC, SUMO2, SUMO3, TNRC6B, SUMO1, NEDD8, COASY, EFHD2, PPME1, TSTA3, RCN1, RAB1A, PSMD5, PNP, MTAP, ENO2, FBXO6, AGPAT2, VCAM1, ITGA4, FN1, APRT, AHCY, CUL3, SIRT7, SUMO4, USP7, DDA1, PRKAG2, BABAM1, TCEAL1,
Protein Size: 693 -
分子量
- 77 kDa
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基因ID
- 8833
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NCBI登录号
- NM_003875, NP_003866
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UniProt
- P49915
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途径
- Ribonucleoside Biosynthetic Process
抗原
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