MDH1 抗体 (Middle Region)
Quick Overview for MDH1 抗体 (Middle Region) (ABIN2783317)
抗原
See all MDH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - Middle Region
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序列
 - NFSCLTRLDH NRAKAQIALK LGVTANDVKN VIIWGNHSST QYPDVNHAKV
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预测反应
 - Cow: 100%, Dog: 93%, Goat: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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产品特性
 - This is a rabbit polyclonal antibody against MDH1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
 - Protein A purified
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免疫原
 - The immunogen is a synthetic peptide directed towards the middle region of human MDH1
 
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应用备注
 - Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 334 AA
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - Lot specific
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缓冲液
 - Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Avoid repeated freeze-thaw cycles.
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储存条件
 - -20 °C
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储存方法
 - For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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                                            : "Selective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo."    in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 7, pp. 1751-8, (2016)         (PubMed).        
: "Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation." in: PLoS ONE, Vol. 8, Issue 5, pp. e64093, (2013) (PubMed).
 
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                                            : "Selective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo."    in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 7, pp. 1751-8, (2016)         (PubMed).        
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- MDH1 (Malate Dehydrogenase 1, NAD (Soluble) (MDH1))
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别名
 - MDH1
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背景
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                        Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH1 is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria.Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MDH-s, MDHA, MGC:1375, MOR2
Protein Interaction Partner: ISG15, UBC, NEDD8, PARK2, HSP90AB1, HSP90AA1, FUS, IQCB1, SDHA, PGM1, LDHA, ESD, Htt, PRDX5, PRDX6, SLC9A3R1, AKT1, TERF2IP, TERF1, TP53, EGFR, MPP3, MDH1, GPD1,
Protein Size: 334 - 
                                            
分子量
 - 36 kDa
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基因ID
 - 4190
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NCBI登录号
 - NM_005917, NP_005908
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UniProt
 - P40925
 
抗原
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