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MDH1 抗体 (Middle Region)

This anti-MDH1 antibody is a 兔 多克隆 antibody detecting MDH1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 兔, 马, 豚鼠, 犬, 斑马鱼 和 山羊. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2783317
发货至: 中国

Quick Overview for MDH1 抗体 (Middle Region) (ABIN2783317)

抗原

See all MDH1 抗体
MDH1 (Malate Dehydrogenase 1, NAD (Soluble) (MDH1))

适用

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人, 小鼠, 大鼠, Cow, 兔, 马, 豚鼠, 犬, 斑马鱼, 山羊

宿主

  • 59
  • 13
  • 5
  • 1

克隆类型

  • 63
  • 14
多克隆

标记

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This MDH1 antibody is un-conjugated

应用范围

  • 69
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Western Blotting (WB)
  • 抗原表位

    • 16
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    Middle Region

    序列

    NFSCLTRLDH NRAKAQIALK LGVTANDVKN VIIWGNHSST QYPDVNHAKV

    预测反应

    Cow: 100%, Dog: 93%, Goat: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

    产品特性

    This is a rabbit polyclonal antibody against MDH1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human MDH1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 334 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Nussbaumer, Asara, Teplytska, Murphy, Logan, Turck, Filiou: "Selective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 7, pp. 1751-8, (2016) (PubMed).

    Povlsen, Løfgren, Dalgas, Birkler, Johannsen, Støttrup, Bøtker: "Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation." in: PLoS ONE, Vol. 8, Issue 5, pp. e64093, (2013) (PubMed).

  • 抗原

    MDH1 (Malate Dehydrogenase 1, NAD (Soluble) (MDH1))

    别名

    MDH1

    背景

    Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH1 is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria.Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MDH-s, MDHA, MGC:1375, MOR2
    Protein Interaction Partner: ISG15, UBC, NEDD8, PARK2, HSP90AB1, HSP90AA1, FUS, IQCB1, SDHA, PGM1, LDHA, ESD, Htt, PRDX5, PRDX6, SLC9A3R1, AKT1, TERF2IP, TERF1, TP53, EGFR, MPP3, MDH1, GPD1,
    Protein Size: 334

    分子量

    36 kDa

    基因ID

    4190

    NCBI登录号

    NM_005917, NP_005908

    UniProt

    P40925
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