PFN1 抗体 (N-Term)
Quick Overview for PFN1 抗体 (N-Term) (ABIN2783306)
抗原
See all PFN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AGWNAYIDNL MADGTCQDAA IVGYKDSPSV WAAVPGKTFV NITPAEVGVL
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预测反应
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 91%
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产品特性
- This is a rabbit polyclonal antibody against PFN1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PFN1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 140 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Reversal of myofibroblastic activation by polyunsaturated fatty acids in valvular interstitial cells from aortic valves. Role of RhoA/G-actin/MRTF signalling." in: Journal of molecular and cellular cardiology, Vol. 74, pp. 127-38, (2014) (PubMed).
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Reversal of myofibroblastic activation by polyunsaturated fatty acids in valvular interstitial cells from aortic valves. Role of RhoA/G-actin/MRTF signalling." in: Journal of molecular and cellular cardiology, Vol. 74, pp. 127-38, (2014) (PubMed).
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- PFN1 (Profilin 1 (PFN1))
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别名
- PFN1
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背景
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PFN1 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome.The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: UBC, FUS, STUB1, SUMO1, NEDD8, MDM2, ASB12, ASB2, ASB1, YWHAQ, SRPK1, ESR1, RAD52, RAD51, ACTB, VCAM1, ITGA4, FN1, ATF2, LIG4, SET, ACAA2, LOC440434, MRPL53, SRPRB, CAND1, CUL3, CDK2, ISG15, ELAVL1, AI837181, Akap12, Csnk1e, Mapk13, UCHL5, WIPF2, LRIF1, M
Protein Size: 140 -
分子量
- 15 kDa
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基因ID
- 5216
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NCBI登录号
- NM_005022, NP_005013
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UniProt
- P07737
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途径
- Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location
抗原
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