BAG3 抗体 (Middle Region)
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北京 101111
Quick Overview for BAG3 抗体 (Middle Region) (ABIN2783302)
抗原
See all BAG3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- NVTRPAAQPS FHQAQKTHYP AQQGEYQTHQ PVYHKIQGDD WEPRPLRAAS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against BAG3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human BAG3
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anti-BCL2-Associated Athanogene 3 (BAG3) (C-Term) antibody
Verified BAG3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) antibodyBAG3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) (AA 380-575) antibodyBAG3 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) (C-Term) antibodyBAG3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) (AA 220-420) antibodyBAG3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) antibodyBAG3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) antibodyBAG3 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 3D8 unconjugated Recombinant Antibody
anti-BCL2-Associated Athanogene 3 (BAG3) (AA 1-575) antibodyBAG3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) (AA 1-575) antibodyBAG3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5A8 unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) (AA 2-577) antibodyBAG3 适用: 小鼠 ELISA, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 575 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
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别名
- BAG3
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背景
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BAG3 inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. BAG3 has anti-apoptotic activity.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BAG-3, BIS, CAIR-1, MGC104307
Protein Interaction Partner: SF3B4, DAZAP2, ARRDC3, LITAF, MAGED1, PDE9A, HSPA8, PHLDB1, HSPB1, HSF1, STUB1, DNAJB6, AMOT, PDLIM7, MLF2, HSPB8, WBP2, UBC, MCM7, HSP90AB1, ETFA, MVP, ACLY, PSAP, PSME1, PSMD12, PSMD9, PSMD8, PSMD5, PSMD3, PSMD2, PSMC5, PSMC3, PSMC2, PSMC1, PSMB5, PSMB4
Protein Size: 575 -
分子量
- 61 kDa
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基因ID
- 9531
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NCBI登录号
- NM_004281, NP_004272
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UniProt
- O95817
抗原
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