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Sep 15 抗体 (Middle Region)

This anti-Sep 15 antibody is a 兔 多克隆 antibody detecting Sep 15 in WB. Suitable for 人, 小鼠, 大鼠, Pig, 斑马鱼 和 Cow.
产品编号 ABIN2783300
发货至: 中国

Quick Overview for Sep 15 抗体 (Middle Region) (ABIN2783300)

抗原

See all Sep 15 (SEP15) 抗体
Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

适用

  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Pig, 斑马鱼, Cow

宿主

  • 4
  • 1

克隆类型

  • 5
多克隆

标记

  • 5
This Sep 15 antibody is un-conjugated

应用范围

  • 5
  • 2
Western Blotting (WB)
  • 抗原表位

    • 2
    • 1
    • 1
    Middle Region

    序列

    SDKPKLFRGL QIKYVRGSDP VLKLLDDNGN IAEELSILKW NTDSVEEFLS

    预测反应

    Cow: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against SEP15. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human SEP15
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 165 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

    别名

    SEP15

    背景

    SEP15 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. The gene that encodes the protein is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Alias Symbols: -
    Protein Interaction Partner: METTL23, UBC, DCUN1D1, CUL3, BAMBI, XRCC6, UGGT2, UGGT1,
    Protein Size: 165

    分子量

    15 kDa

    基因ID

    9403

    NCBI登录号

    NM_004261, NP_004252

    UniProt

    O60613
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