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TCAP 抗体 (Middle Region)

This anti-TCAP antibody (ABIN2783291) is a Rabbit Polyclonal antibody detecting TCAP in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Goat, Rabbit.
产品编号 ABIN2783291
发货至: 中国

Quick Overview for TCAP 抗体 (Middle Region) (ABIN2783291)

抗原

See all TCAP 抗体
TCAP (Titin-Cap (Telethonin) (TCAP))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 山羊, 兔

宿主

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克隆类型

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多克隆

标记

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This TCAP antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    IQLQELLALE TALGGQCVDR QEVAEITKQL PPVVPVSKPG ALRRSLSRSM

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against TCAP. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human TCAP
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 167 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    TCAP (Titin-Cap (Telethonin) (TCAP))

    别名

    TCAP

    背景

    Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CMD1N, LGMD2G, T-cap, TELE, telethonin
    Protein Interaction Partner: TRIM63, TRIM55, RELA, FYN, FAS, ATXN1, MDM2, TTN, PDPK1, MYOZ3, ANKRD2, MYOZ1, MSTN, MYOZ2,
    Protein Size: 167

    分子量

    19 kDa

    基因ID

    8557

    NCBI登录号

    NM_003673, NP_003664

    UniProt

    O15273
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