TCAP 抗体 (Middle Region)
Quick Overview for TCAP 抗体 (Middle Region) (ABIN2783291)
抗原
See all TCAP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- IQLQELLALE TALGGQCVDR QEVAEITKQL PPVVPVSKPG ALRRSLSRSM
-
预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
-
产品特性
- This is a rabbit polyclonal antibody against TCAP. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Protein A purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TCAP
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 167 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- TCAP (Titin-Cap (Telethonin) (TCAP))
-
别名
- TCAP
-
背景
-
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMD1N, LGMD2G, T-cap, TELE, telethonin
Protein Interaction Partner: TRIM63, TRIM55, RELA, FYN, FAS, ATXN1, MDM2, TTN, PDPK1, MYOZ3, ANKRD2, MYOZ1, MSTN, MYOZ2,
Protein Size: 167 -
分子量
- 19 kDa
-
基因ID
- 8557
-
NCBI登录号
- NM_003673, NP_003664
-
UniProt
- O15273
抗原
-