CRYAB 抗体 (C-Term)
Quick Overview for CRYAB 抗体 (C-Term) (ABIN2783274)
抗原
See all CRYAB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 92%
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产品特性
- This is a rabbit polyclonal antibody against CRYAB. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CRYAB
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 175 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CRYAB (Crystallin, alpha B (CRYAB))
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别名
- CRYAB
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背景
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Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.
Alias Symbols: CRYA2, CTPP2, HSPB5
Protein Interaction Partner: CRYAB, CRYAA, KRTAP19-5, KRTAP8-1, TRAPPC6A, MRPL11, TNPO2, ACOT7, HSPB1, CASP7, CASP3, CASP2, PIDD1, DDX20, CRADD, B2M, APOC2, XIAP, CASP12, SOD1, HSPB2, HBA1, CASP9, CASP8, CASP6, ASB5, SMAD4, TRIM33, UBC, CCL22, CTNNB1, CRYGD, CDH1, SNCA, GFAP, FGF2, F
Protein Size: 175 -
分子量
- 20 kDa
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基因ID
- 1410
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NCBI登录号
- NM_001885
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UniProt
- P02511
抗原
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