CAMLG 抗体 (N-Term)
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北京 101111
Quick Overview for CAMLG 抗体 (N-Term) (ABIN2783272)
抗原
See all CAMLG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LLMNSEQRIN RIMGFHRPGS GAEEESQTKS KQQDSDKLNS LSVPSVSKRV
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 85%
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产品特性
- This is a rabbit polyclonal antibody against CAMLG. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CAMLG
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anti-Calcium Modulating Ligand (CAMLG) (AA 19-184) antibody
CAMLG 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium Modulating Ligand (CAMLG) antibodyCAMLG 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Modulating Ligand (CAMLG) (AA 1-190) antibodyCAMLG 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Modulating Ligand (CAMLG) (AA 1-187) antibodyCAMLG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium Modulating Ligand (CAMLG) (AA 1-189) antibodyCAMLG 适用: 人 WB, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Modulating Ligand (CAMLG) antibodyKD Validated CAMLG 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB7950 unconjugated
anti-Calcium Modulating Ligand (CAMLG) (AA 1-296) antibodyCAMLG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium Modulating Ligand (CAMLG) (AA 1-296) antibodyCAMLG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Calcium Modulating Ligand (CAMLG) (AA 1-100) antibodyCAMLG 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F12 unconjugated
anti-Calcium Modulating Ligand (CAMLG) (AA 1-188) antibodyCAMLG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 296 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CAMLG (Calcium Modulating Ligand (CAMLG))
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别名
- CAMLG
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背景
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The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. CAMLG functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
Alias Symbols: CAML, MGC163197
Protein Interaction Partner: KCNA2, TMUB1, TNFRSF13B, UBC, RNF122, PKHD1, EGFR, PPIB, IER3,
Protein Size: 296 -
分子量
- 33 kDa
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基因ID
- 819
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NCBI登录号
- NM_001745, NP_001736
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UniProt
- P49069
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途径
- EGFR Signaling Pathway
抗原
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