ATP5B 抗体 (C-Term)
Quick Overview for ATP5B 抗体 (C-Term) (ABIN2783269)
抗原
See all ATP5B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- MGKLVPLKET IKGFQQILAG EYDHLPEQAF YMVGPIEEAV AKADKLAEEH
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against ATP5B. It was validated on Western Blot using a cell lysate as a positive control. Catalog ABIN973616 can be used a blocking peptide for this product.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ATP5B
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 529 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Elevated mitochondrial biogenesis in skeletal muscle is associated with testosterone-induced body weight loss in male mice." in: FEBS letters, Vol. 588, Issue 10, pp. 1935-41, (2014) (PubMed).
: "Diggin' on u(biquitin): a novel method for the identification of physiological E3 ubiquitin ligase substrates." in: Cell biochemistry and biophysics, Vol. 67, Issue 1, pp. 127-38, (2013) (PubMed).
: "Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: a possible role for SirT3 activation." in: Mitochondrion, Vol. 13, Issue 6, pp. 637-46, (2013) (PubMed).
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: "Elevated mitochondrial biogenesis in skeletal muscle is associated with testosterone-induced body weight loss in male mice." in: FEBS letters, Vol. 588, Issue 10, pp. 1935-41, (2014) (PubMed).
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- ATP5B (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, beta Polypeptide (ATP5B))
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别名
- ATP5B
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背景
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ATP5B is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). ATP5B is the beta subunit of the catalytic core.This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ATPMB, ATPSB, MGC5231
Protein Interaction Partner: FUS, FDX1, ATP5A1, HUWE1, ATPAF2, TRIM63, TRIM55, SPRTN, STAU1, GRSF1, UBC, MDM2, ASB5, ASB11, SUZ12, RNF2, EZH2, BMI1, GBP1, ADRB2, TERT, vpu, UBL4A, WHSC1, VCAM1, PPP1CC, ITGA4, FN1, ESR1, ATF2, BTK, YWHAE, SUMO2, CA9, FMNL1, ATP5O, ATP6V1B2, ATP5C1, AT
Protein Size: 529 -
分子量
- 52 kDa
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基因ID
- 506
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NCBI登录号
- NM_001686, NP_001677
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UniProt
- P06576
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途径
- Proton Transport, Ribonucleoside Biosynthetic Process
抗原
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