Atp5f1b (N-Term) 抗体
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北京 101111
Quick Overview for Atp5f1b (N-Term) 抗体 (ABIN2783268)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- ATP5F1B Antibody - N-terminal region
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序列
- PIKIPVGPET LGRIMNVIGE PIDERGPIKT KQFAPIHAEA PEFMEMSVEQ
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against ATP5B. It was validated on Western Blot and immunohistochemistry. Catalog ABIN973615 can be used a blocking peptide for this product.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ATP5B
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48185-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Up-regulation of key microRNAs, and inverse down-regulation of their predicted oxidative phosphorylation target genes, during aging in mouse brain." in: Neurobiology of aging, Vol. 32, Issue 5, pp. 944-55, (2011) (PubMed).
: "Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease." in: The Journal of clinical investigation, Vol. 121, Issue 4, pp. 1508-18, (2011) (PubMed).
: "Protein targets for carbonylation by 4-hydroxy-2-nonenal in rat liver mitochondria." in: Journal of proteomics, Vol. 74, Issue 11, pp. 2370-9, (2011) (PubMed).
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- Atp5f1b
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背景
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Targeted Subunit: beta, mitochondrial
Background Information: This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core.
Gene Name: ATP synthase F1 subunit beta
Alternative Symbols: ATP5B, ATPMB, ATPSB, HEL-S-271
Protein Name: ATP synthase subunit beta, mitochondrial
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分子量
- 57 kDa
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基因ID
- 506
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NCBI登录号
- NP_001677
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UniProt
- P06576
抗原
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