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Atp5f1b (N-Term) 抗体

Cited in 3+ publications. The 兔 多克隆 anti-Atp5f1b antibody (ABIN2783268) specifically detects Atp5f1b in WB 和 IHC. The antibody is reactive with 小鼠, 人, 大鼠, Pig, 斑马鱼, Saccharomyces cerevisiae, 兔, 马, 犬 和 Cow samples.
产品编号 ABIN2783268
发货至: 中国
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Quick Overview for Atp5f1b (N-Term) 抗体 (ABIN2783268)

抗原

Atp5f1b

适用

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小鼠, 人, 大鼠, Pig, 斑马鱼, Saccharomyces cerevisiae, 兔, 马, 犬, Cow

宿主

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兔

克隆类型

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多克隆

标记

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非结合性

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    原理

    ATP5F1B Antibody - N-terminal region

    序列

    PIKIPVGPET LGRIMNVIGE PIDERGPIKT KQFAPIHAEA PEFMEMSVEQ

    预测反应

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against ATP5B. It was validated on Western Blot and immunohistochemistry. Catalog ABIN973615 can be used a blocking peptide for this product.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ATP5B
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48185-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Li, Bates, An, Terry, Wang: "Up-regulation of key microRNAs, and inverse down-regulation of their predicted oxidative phosphorylation target genes, during aging in mouse brain." in: Neurobiology of aging, Vol. 32, Issue 5, pp. 944-55, (2011) (PubMed).

    Zischka, Lichtmannegger, Schmitt, Jägemann, Schulz, Wartini, Jennen, Rust, Larochette, Galluzzi, Chajes, Bandow, Gilles, DiSpirito, Esposito, Goettlicher, Summer, Kroemer: "Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease." in: The Journal of clinical investigation, Vol. 121, Issue 4, pp. 1508-18, (2011) (PubMed).

    Guo, Prokai-Tatrai, Nguyen, Rauniyar, Ughy, Prokai: "Protein targets for carbonylation by 4-hydroxy-2-nonenal in rat liver mitochondria." in: Journal of proteomics, Vol. 74, Issue 11, pp. 2370-9, (2011) (PubMed).

  • 抗原

    Atp5f1b

    背景

    Targeted Subunit: beta, mitochondrial

    Background Information: This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core.

    Gene Name: ATP synthase F1 subunit beta

    Alternative Symbols: ATP5B, ATPMB, ATPSB, HEL-S-271

    Protein Name: ATP synthase subunit beta, mitochondrial

    分子量

    57 kDa

    基因ID

    506

    NCBI登录号

    NP_001677

    UniProt

    P06576
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