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APEH 抗体 (N-Term)

This anti-APEH antibody is a 兔 多克隆 antibody detecting APEH in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 马, 斑马鱼 和 犬.
产品编号 ABIN2783264
发货至: 中国

Quick Overview for APEH 抗体 (N-Term) (ABIN2783264)

抗原

See all APEH 抗体
APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

适用

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人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 马, 斑马鱼, 犬

宿主

  • 50

克隆类型

  • 50
多克隆

标记

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This APEH antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    VYEDDCFGCL SWSHSETHLL YVAEKKRPKA ESFFQTKALD VSASDDEIAR

    预测反应

    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

    产品特性

    This is a rabbit polyclonal antibody against APEH. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human APEH
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 732 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

    别名

    APEH

    背景

    APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ACPH, APH, D3F15S2, D3S48E, DNF15S2, MGC2178, OPH, AARE
    Protein Interaction Partner: IST1, UBC, LGALS8, APEH, SNX6, CAND1, TOLLIP, CYHR1, JMJD6, HSPA4L, IPO7, DNM1L, VPS26A, NMI, H1FX, ZYX, TBCD, TARS, STAT1, SHMT2, SHMT1, PPM1G, SERPINE2, PAWR, LAMP2, KARS, HIST1H1C, GARS, CTTN, CARS, PREPL, SHBG, UBA5, TMEM62,
    Protein Size: 732

    分子量

    81 kDa

    基因ID

    327

    NCBI登录号

    NM_001640, NP_001631

    UniProt

    P13798
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