Adenylate Kinase 1 抗体 (N-Term)
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北京 101111
Quick Overview for Adenylate Kinase 1 抗体 (N-Term) (ABIN2783244)
抗原
See all Adenylate Kinase 1 (AK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- AK1 Antibody - N-terminal region
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序列
- HLSTGDLLRS EVSSGSARGK KLSEIMEKGQ LVPLETVLDM LRDAMVAKVN
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预测反应
- Cow: 92%, Dog: 92%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 92%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against AK1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human AK1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48148-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Adenylate Kinase 1 (AK1)
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别名
- AK1
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背景
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Background Information: Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Adenylate kinase 1
Alternative Symbols: HTL-S-58j
Protein Name: Adenylate kinase isoenzyme 1
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分子量
- 22kDa
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基因ID
- 203
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NCBI登录号
- NP_000467
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UniProt
- P00568
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途径
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
抗原
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