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Adenylate Kinase 1 抗体 (N-Term)

This anti-Adenylate Kinase 1 antibody is a 兔 多克隆 antibody detecting Adenylate Kinase 1 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 绵羊, 马 和 斑马鱼.
产品编号 ABIN2783244
发货至: 中国

Quick Overview for Adenylate Kinase 1 抗体 (N-Term) (ABIN2783244)

抗原

See all Adenylate Kinase 1 (AK1) 抗体
Adenylate Kinase 1 (AK1)

适用

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人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 绵羊, 马, 斑马鱼

宿主

  • 81
  • 10
  • 6

克隆类型

  • 88
  • 9
多克隆

标记

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This Adenylate Kinase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 17
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    N-Term

    序列

    HLSTGDLLRS EVSSGSARGK KLSEIMEKGQ LVPLETVLDM LRDAMVAKVN

    预测反应

    Cow: 92%, Dog: 92%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 92%, Zebrafish: 77%

    产品特性

    This is a rabbit polyclonal antibody against AK1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human AK1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 194 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Adenylate Kinase 1 (AK1)

    别名

    AK1

    背景

    Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: UBC, IDH1, APP, TERF2IP, TINF2, TERF1, TRIM63, FHL2, KMT2C,
    Protein Size: 194

    分子量

    22 kDa

    基因ID

    203

    NCBI登录号

    NM_000476, NP_000467

    UniProt

    P00568

    途径

    Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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