HADHB 抗体 (C-Term)
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北京 101111
Quick Overview for HADHB 抗体 (C-Term) (ABIN2783232)
抗原
See all HADHB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LLLGPTYATP KVLEKAGLTM NDIDAFEFHE AFSGQILANF KAMDSDWFAE
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Yeast: 83%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against HADHB. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human HADHB
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anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 34-270) antibody
HADHB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 1-474) antibodyHADHB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 1-474) antibodyHADHB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 351-400) antibodyHADHB 适用: 人, 小鼠, 大鼠, Pig, 斑马鱼, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) antibodyHADHB 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 1-259) antibodyHADHB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 35-283) antibodyHADHB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) antibody (FITC)HADHB 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (N-Term) antibodyHADHB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 315-342), (C-Term) antibodyHADHB 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22183 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 474 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling." in: American journal of physiology. Heart and circulatory physiology, Vol. 311, Issue 1, pp. H64-75, (2016) (PubMed).
: "Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 33652-61, (2010) (PubMed).
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: "TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling." in: American journal of physiology. Heart and circulatory physiology, Vol. 311, Issue 1, pp. H64-75, (2016) (PubMed).
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- HADHB (Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB))
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别名
- HADHB
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背景
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HADHB is the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in HADHB gene result in trifunctional protein deficiency. The protein can also bind RNA and decreases the stability of some mRNAs.This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found, however, their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC87480, MSTP029, TP-BETA, ECHB, MTPB
Protein Interaction Partner: HUWE1, TP53, TUBG1, SUMO2, SUMO3, UBC, PARK2, PPP6R1, ADRB2, CSNK2A2, PAN2, ATF2, vpu, TIMM8B, COX17, IQCB1, SUOX, CHCHD4, TUBB1, RPS8, OPA1, HSP90AB1, HADHA, DES, GRK5, FBXO6, CDK2, LEO1, RTF1, TK1, SMN1, PSMA3, GRB7, RCC1, CDKN1A, ANXA7, Edc4, MYC, SQST
Protein Size: 474 -
分子量
- 47 kDa
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基因ID
- 3032
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NCBI登录号
- NM_000183, NP_000174
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UniProt
- P55084
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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