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PAX8 抗体 (N-Term)

This anti-PAX8 antibody is a 兔 多克隆 antibody detecting PAX8 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2783221
发货至: 中国

Quick Overview for PAX8 抗体 (N-Term) (ABIN2783221)

抗原

See all PAX8 抗体
PAX8 (Paired Box 8 (PAX8))

适用

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  • 1
  • 1
人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼

宿主

  • 90
  • 60
  • 1

克隆类型

  • 90
  • 61
多克隆

标记

  • 72
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  • 1
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  • 1
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This PAX8 antibody is un-conjugated

应用范围

  • 101
  • 67
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  • 6
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 50
    • 9
    • 9
    • 6
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    KSLSPGHTLI PSSAVTPPES PQSDSLGSTY SINGLLGIAQ PGSDKRKMDD

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against PAX8. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PAX8
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 450 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • 抗原

    PAX8 (Paired Box 8 (PAX8))

    别名

    PAX8

    背景

    PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in its gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: -
    Protein Interaction Partner: SERINC1, ANXA7, PKM, CXCL9, CHUK, POU2AF1, WBP2, SMAD3, EP300, NKX2-1, ID2,
    Protein Size: 450

    分子量

    48 kDa

    基因ID

    7849

    NCBI登录号

    NM_003466, NP_003457

    UniProt

    Q06710

    途径

    Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
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