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REC8 抗体 (N-Term)

This anti-REC8 antibody is a 兔 多克隆 antibody detecting REC8 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠 和 马.
产品编号 ABIN2783199
发货至: 中国

Quick Overview for REC8 抗体 (N-Term) (ABIN2783199)

抗原

See all REC8 抗体
REC8 (REC8 Homolog (Yeast) (REC8))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马

宿主

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克隆类型

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多克隆

标记

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This REC8 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    QLQIGVIRVY SQQCQYLVED IQHILERLHR AQLQIRIDME TELPSLLLPN

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against REC8. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human REC8
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 547 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    REC8 (REC8 Homolog (Yeast) (REC8))

    别名

    REC8

    背景

    REC8 is required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
    Alias Symbols: HR21spB, MGC950, REC8L1, Rec8p
    Protein Interaction Partner: SYCP3, SMC3, SMC1A,
    Protein Size: 547

    分子量

    62 kDa

    基因ID

    9985

    NCBI登录号

    NM_005132, NP_005123

    UniProt

    O95072
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