Arrestin 3 抗体 (Middle Region)
Quick Overview for Arrestin 3 抗体 (Middle Region) (ABIN2783190)
抗原
See all Arrestin 3 (ARRB2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- RLVIRKVQFA PEKPGPQPSA ETTRHFLMSD RSLHLEASLD KELYYHGEPL
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
-
产品特性
- This is a rabbit polyclonal antibody against ARRB2. It was validated on Western Blot and immunohistochemistry.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ARRB2
-
-
anti-Arrestin, beta 2 (ARRB2) (Internal Region) antibody
Verified ARRB2 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-409) antibodyARRB2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-400) antibodyARRB2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 300-409) antibodyARRB2 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 222-369) antibodyARRB2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (C-Term) antibodyARRB2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (Middle Region) antibodyARRB2 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 251-418) antibodyARRB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 262-430) antibodyARRB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 2 (ARRB2) (AA 264-298) antibodyARRB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB53542 unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 409 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
-
别名
- ARRB2
-
背景
-
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: ARB2, ARR2, DKFZp686L0365, BARR2
Protein Interaction Partner: UBC, SRC, MAPK9, INSR, AKT1, USP33, ADRB2, TBXA2R, CYTH1, PTGDS, BAI1, LIMK1, CFL1, CSK, AGTR1, MAP2K4, MAPK10, MAP3K5, GCG, NFKBIA, MDM2, IGF1R, CLTC, ADRB1, HIPK3, EDNRA, gag-pol, ARRDC3, ARRDC4, SIRT1, PDE4D, Mlnr, Trhr, C5AR1, SLC9A5, AP2M1, HCRTR1, F
Protein Size: 409 -
分子量
- 46 kDa
-
基因ID
- 409
-
NCBI登录号
- NM_199004, NP_945355
-
UniProt
- P32121
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
抗原
-
