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NDE1 抗体 (Middle Region)

NDE1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783161
发货至: 中国
  • 抗原 See all NDE1 抗体
    NDE1
    抗原表位
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
    宿主
    • 16
    • 3
    克隆类型
    • 16
    • 3
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    This NDE1 antibody is un-conjugated
    应用范围
    • 16
    • 13
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    AHRGPSSSLN TPGSFRRGLD DSTGGTPLTP AARISALNIV GDLLRKVGAL
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    产品特性
    This is a rabbit polyclonal antibody against NDE1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human NDE1
    Top Product
    Discover our top product NDE1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 335 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Burdick, Kamiya, Hodgkinson, Lencz, DeRosse, Ishizuka, Elashvili, Arai, Goldman, Sawa, Malhotra: "Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding." in: Human molecular genetics, Vol. 17, Issue 16, pp. 2462-73, (2008) (PubMed).

  • 抗原
    NDE1
    别名
    NDE1 (NDE1 产品)
    别名
    2810027M15Rik antibody, AU042936 antibody, AW822251 antibody, Nude antibody, mNudE antibody, HOM-TES-87 antibody, LIS4 antibody, NDE antibody, NUDE antibody, NUDE1 antibody, fb82g01 antibody, im:7141877 antibody, wu:fb82g01 antibody, zgc:114109 antibody, nudE neurodevelopment protein 1 antibody, Nde1 antibody, NDE1 antibody, nde1 antibody
    背景
    NDE1 is required for centrosome duplication and formation and function of the mitotic spindle. It is essential for the development of the cerebral cortex. NDE1 may regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex
    Alias Symbols: FLJ20101, HOM-TES-87, NUDE, NUDE1, LIS4
    Protein Interaction Partner: FAM9B, LZTS2, USHBP1, NDEL1, ZNF398, NDE1, WAC, UBQLN1, MED4, DISC1, TFIP11, CEP250, NDC80, ARNT2, BZRAP1, MKRN3, TTC1, TRIM27, REL, HOXA2, GOLGA2, AR, YWHAQ, PAFAH1B1, ZNF365, YWHAG, TUBG1, MAPK1, CDK1,
    Protein Size: 335
    分子量
    38 kDa
    基因ID
    54820
    NCBI登录号
    NM_017668, NP_060138
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