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ATRX 抗体 (C-Term)

ATRX 适用: 人, 兔, Pig, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783135
发货至: 中国
  • 抗原 See all ATRX 抗体
    ATRX (helicase 2, X-linked (ATRX))
    抗原表位
    • 12
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 61
    • 17
    • 3
    • 2
    • 1
    • 1
    人, 兔, Pig, 犬
    宿主
    • 40
    • 23
    • 1
    克隆类型
    • 37
    • 27
    多克隆
    标记
    • 39
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATRX antibody is un-conjugated
    应用范围
    • 38
    • 29
    • 21
    • 18
    • 16
    • 11
    • 11
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    DQSDETSEDD KKQSKKGTEE KKKPSDFKKK VIKMEQQYES SSDGTEKLPE
    预测反应
    Dog: 88%, Human: 100%, Pig: 93%, Rabbit: 75%
    产品特性
    This is a rabbit polyclonal antibody against ATRX. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human ATRX
    Top Product
    Discover our top product ATRX Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ATRX (helicase 2, X-linked (ATRX))
    别名
    ATRX (ATRX 产品)
    别名
    ATR2 antibody, JMS antibody, MRXHF1 antibody, RAD54 antibody, RAD54L antibody, SFM1 antibody, SHS antibody, XH2 antibody, XNP antibody, ZNF-HX antibody, 4833408C14Rik antibody, AI447451 antibody, DXHXS6677E antibody, HP1-BP38 antibody, Hp1bp2 antibody, Hp1bp38 antibody, MRXS3 antibody, Rad54 antibody, Xnp antibody, atrx antibody, rad54 antibody, atrxl antibody, wu:fb26e12 antibody, wu:fb52h08 antibody, wu:fb72g09 antibody, wu:fb94e07 antibody, zgc:66223 antibody, ATRX, chromatin remodeler antibody, alpha thalassemia/mental retardation syndrome X-linked L homeolog antibody, alpha thalassemia/mental retardation syndrome X-linked homolog (human) antibody, ATRX antibody, Atrx antibody, atrx.L antibody, atrx antibody
    背景
    The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Protein Interaction Partner: SUMO2, SUMO3, RAD51, H3F3A, PRKDC, PML, NBN, MRE11A, HIST1H1C, XRCC6, DAXX, SUPT16H, RAD50, HIST1H4J, HIST2H2BE, HIST1H2BL, HIST1H2AB, XRCC5, TP53, SSRP1, RPA1, RAD9A, RAD1, ZNF512B, UL82, NEK1, BLM, HIST2H3C, ZBED1, UBC, SVIL, CALM1, WRN, HIST1H3A, CBX5,
    Protein Size: 1350
    分子量
    148 kDa
    基因ID
    546
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