PSMC3IP 抗体 (Middle Region)
Quick Overview for PSMC3IP 抗体 (Middle Region) (ABIN2783050)
抗原
See all PSMC3IP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RLKNIKAATN HVTPEEKEQV YRERQKYCKE WRKRKRMATE LSDAILEGYP
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预测反应
- Cow: 93%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against PSMC3IP. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PSMC3IP
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anti-PSMC3 Interacting Protein (PSMC3IP) (AA 1-217) antibody
PSMC3IP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-PSMC3 Interacting Protein (PSMC3IP) (AA 143-192) antibodyPSMC3IP 适用: 小鼠, 人, 犬, 马, 兔, 山羊, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-PSMC3 Interacting Protein (PSMC3IP) (C-Term) antibodyPSMC3IP 适用: 小鼠, 人, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, 猴, 小鸡, 非洲爪蟾, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-PSMC3 Interacting Protein (PSMC3IP) (C-Term) antibodyPSMC3IP 适用: 小鼠, 人, 大鼠, 犬, Cow, 斑马鱼, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 217 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))
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别名
- PSMC3IP
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背景
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PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
Alias Symbols: GT198, HOP2, TBPIP, ODG3, HUMGT198A
Protein Interaction Partner: PSMC3, PSMC3IP, THRB, ESR2, AR, RXRA, NR3C1,
Protein Size: 217 -
分子量
- 25 kDa
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基因ID
- 29893
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NCBI登录号
- NM_016556, NP_057640
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UniProt
- Q9P2W1
抗原
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