MORF4L1 抗体 (Middle Region)
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- 抗原 See all MORF4L1 抗体
- MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MORF4L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PEELKPWLVD DWDLITRQKQ LFYLPAKKNV DSILEDYANY KKSRGNTDNK
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 93%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against Morf4l1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product MORF4L1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 362 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))
- 别名
- Morf4l1 (MORF4L1 产品)
- 别名
- Eaf3 antibody, HsT17725 antibody, MEAF3 antibody, MORFRG15 antibody, MRG15 antibody, S863-6 antibody, TEG-189 antibody, Tex189 antibody, mKIAA4002 antibody, MORF4L2 antibody, CG6363 antibody, DmMRG15 antibody, Dmel\\CG6363 antibody, Dmrg15 antibody, Mrg15 antibody, dMRG15 antibody, dMrg15 antibody, l(3)j6A3 antibody, zgc:92289 antibody, mortality factor 4 like 1 antibody, MORF-related gene 15 antibody, MRG15 antibody, mortality factor 4 like 1 S homeolog antibody, MORF4L1 antibody, Morf4l1 antibody, MRG15 antibody, CpipJ_CPIJ013367 antibody, morf4l1.S antibody, morf4l1 antibody
- 背景
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Morf4l1 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
Alias Symbols: KIAA4002, MGC102415, MGC103105, MGC118047, MORFRG15, MRG15, TEG-189, Tex189, mKIAA4002
Protein Interaction Partner: Nanog, Hdac1, Phf12, Sin3b, Rb1, MRFAP1, Vezf1, Rnf2, Kdm5b, SIN3A, TLE1, PFN2,
Protein Size: 362 - 分子量
- 41 kDa
- 基因ID
- 21761
- NCBI登录号
- NM_001039147, NP_001034236
- UniProt
- P60762
- 途径
- Chromatin Binding
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