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MORF4L1 抗体 (Middle Region)

This anti-MORF4L1 antibody is a 兔 多克隆 antibody detecting MORF4L1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 和 Pig.
产品编号 ABIN2783048
发货至: 中国

Quick Overview for MORF4L1 抗体 (Middle Region) (ABIN2783048)

抗原

See all MORF4L1 抗体
MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig

宿主

  • 54
  • 3
  • 2

克隆类型

  • 56
  • 3
多克隆

标记

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This MORF4L1 antibody is un-conjugated

应用范围

  • 43
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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    PEELKPWLVD DWDLITRQKQ LFYLPAKKNV DSILEDYANY KKSRGNTDNK

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 93%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against Morf4l1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide corresponding to a region of Mouse
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 362 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))

    别名

    Morf4l1

    背景

    Morf4l1 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
    Alias Symbols: KIAA4002, MGC102415, MGC103105, MGC118047, MORFRG15, MRG15, TEG-189, Tex189, mKIAA4002
    Protein Interaction Partner: Nanog, Hdac1, Phf12, Sin3b, Rb1, MRFAP1, Vezf1, Rnf2, Kdm5b, SIN3A, TLE1, PFN2,
    Protein Size: 362

    分子量

    41 kDa

    基因ID

    21761

    NCBI登录号

    NM_001039147, NP_001034236

    UniProt

    P60762

    途径

    Chromatin Binding
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