MAFK 抗体 (N-Term)
Quick Overview for MAFK 抗体 (N-Term) (ABIN2783019)
抗原
See all MAFK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- KEAGENAPVL SDDELVSMSV RELNQHLRGL TKEEVTRLKQ RRRTLKNRGY
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 79%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against MAFK. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAFK
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anti-Transcription Factor MafK (MAFK) antibody
MAFK 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 8C5 unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 斑马鱼, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠, 豚鼠, Hamster, 猴, 小鸡, 非洲爪蟾, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 156 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAFK (Transcription Factor MafK (MAFK))
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别名
- MAFK
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背景
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The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2. NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, PBGD and FECH. NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of bZIP proteins. Maf homodimers suppress transcription at NFE2 sites.The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD, MIM 176000) and ferrochelatase (FECH, MIM 177000). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM].
Alias Symbols: FLJ32205, MGC71717, NFE2U, P18
Protein Interaction Partner: NFE2L2, SMAD3, PARP1, HIF1A, UBC, SUMO2, Bach1, HDAC3, HDAC2, HDAC1, CREBBP, RELA, KAT6A, TP53, BACH2, NFE2L3, NFE2, MARS, MAFK, NFE2L1, HOXD12,
Protein Size: 156 -
分子量
- 17 kDa
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基因ID
- 7975
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NCBI登录号
- NM_002360, NP_002351
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UniProt
- O60675
抗原
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