MGA (C-Term) 抗体
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- 抗原
- MGA
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抗原表位
- C-Term
- 适用
- 人, Cow, 犬, 马, 小鼠, Pig, 兔, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB)
- 序列
- ASLQMKRESQ NPDQKDETNS IKREQETKKV LQSEGEAVDP EANVIKQNSG
- 预测反应
- Cow: 92%, Dog: 85%, Horse: 92%, Human: 100%, Mouse: 79%, Pig: 92%, Rabbit: 79%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against MGA. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MGA
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MGA
- 背景
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MGA functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes and functions as a repressor or an activator. It binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. It suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. It function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor
Protein Interaction Partner: SUMO2, SUMO3, EED, RNF2, MAX, SMAD1, LSM8, UBC, CD2BP2, CBX2, PCGF6, RYBP, PCGF3, YAF2, CBX4, CBX3, E2F4, E2F3, E2F1,
Protein Size: 697 - 分子量
- 76 kDa
- 基因ID
- 23269
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