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MGA (C-Term) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in WB. Suitable for 人, Cow, 犬, 马, 小鼠, Pig, 兔 和 大鼠.
产品编号 ABIN2783018
发货至: 中国

Quick Overview for MGA (C-Term) 抗体 (ABIN2783018)

抗原

MGA

适用

人, Cow, 犬, 马, 小鼠, Pig, 兔, 大鼠

宿主

  • 4
  • 1

克隆类型

  • 4
  • 1
多克隆

标记

  • 5
非结合性

应用范围

  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    ASLQMKRESQ NPDQKDETNS IKREQETKKV LQSEGEAVDP EANVIKQNSG

    预测反应

    Cow: 92%, Dog: 85%, Horse: 92%, Human: 100%, Mouse: 79%, Pig: 92%, Rabbit: 79%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against MGA. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human MGA
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MGA

    背景

    MGA functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes and functions as a repressor or an activator. It binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. It suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. It function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor
    Protein Interaction Partner: SUMO2, SUMO3, EED, RNF2, MAX, SMAD1, LSM8, UBC, CD2BP2, CBX2, PCGF6, RYBP, PCGF3, YAF2, CBX4, CBX3, E2F4, E2F3, E2F1,
    Protein Size: 697

    分子量

    76 kDa

    基因ID

    23269
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