FTO 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for FTO 抗体 (Middle Region) (ABIN2782981)
抗原
See all FTO 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
原理
- FTO Antibody - middle region
-
序列
- WWCQPMAQLE ALWKKMEGVT NAVLHEVKRE GLPVEQRNEI LTAILASLTA
-
预测反应
- Dog: 86%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
-
产品特性
- This is a rabbit polyclonal antibody against FTO. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FTO
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47474-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- FTO (Fat Mass and Obesity-Associated (FTO))
-
别名
- FTO
-
背景
-
Background Information: The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death.
Gene Name: Fat mass and obesity associated
Alternative Symbols: GDFD, ALKBH9, BMIQ14
Protein Name: Alpha-ketoglutarate-dependent dioxygenase FTO
-
分子量
- 58kDa
-
基因ID
- 79068
-
NCBI登录号
- NP_001073901
-
UniProt
- Q9C0B1
抗原
-