FTO 抗体 (Middle Region)
Quick Overview for FTO 抗体 (Middle Region) (ABIN2782981)
抗原
See all FTO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- WWCQPMAQLE ALWKKMEGVT NAVLHEVKRE GLPVEQRNEI LTAILASLTA
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预测反应
- Dog: 86%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against FTO. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FTO
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 505 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FTO (Fat Mass and Obesity-Associated (FTO))
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别名
- FTO
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背景
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The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death.
Alias Symbols: KIAA1752, MGC5149
Protein Interaction Partner: UBC, SUMO1, NEDD8, BCCIP, CNDP2, DAK, NDRG1, NPEPPS, SLC9A3R1, CTSA, PEPD, MVD, LDHB, LDHA, EEF2, CKB,
Protein Size: 505 -
分子量
- 58 kDa
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基因ID
- 79068
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NCBI登录号
- NM_001080432, NP_001073901
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UniProt
- Q9C0B1
抗原
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