FTO 抗体 (N-Term)
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北京 101111
Quick Overview for FTO 抗体 (N-Term) (ABIN2782980)
抗原
See all FTO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Fto Antibody - N-terminal region
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序列
- MKRVQTAEER EREAKKLRLL EELEDTWLPY LTPKDDEFYQ QWQLKYPKLV
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Yeast: 90%
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产品特性
- This is a rabbit polyclonal antibody against Fto. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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anti-Fat Mass and Obesity-Associated (FTO) (AA 279-505) antibody
FTO 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 4G9 unconjugated Recombinant Antibody
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人 WB, IHC, ELISA, IP 宿主: 小鼠 Monoclonal AG103 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 小鼠 WB, IHC, ELISA, IP 宿主: 小鼠 Monoclonal FT62-6 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyKO Validated FTO 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3630 unconjugated Recombinant Antibody
anti-Fat Mass and Obesity-Associated (FTO) antibodyKO Validated FTO 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3625 unconjugated Recombinant Antibody
anti-Fat Mass and Obesity-Associated (FTO) antibodyKO Validated FTO 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2700 unconjugated Recombinant Antibody
anti-Fat Mass and Obesity-Associated (FTO) antibodyKO Validated FTO 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB3740 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) (AA 1-30), (N-Term) antibodyFTO 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21572 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47473-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- FTO (Fat Mass and Obesity-Associated (FTO))
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别名
- Fto
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背景
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Background Information: Fto is a dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Fto has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Fto has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Fto has no activity towards 1-methylguanine and no detectable activity towards double-stranded DNA. Fto requires molecular oxygen, alpha-ketoglutarate and iron. Fto contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Fto contributes to the regulation of body size and body fat accumulation.
Gene Name: Fat mass and obesity associated
Alternative Symbols: AW743446, mKIAA1752
Protein Name: Alpha-ketoglutarate-dependent dioxygenase FTO
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分子量
- 58kDa
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基因ID
- 26383
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NCBI登录号
- NP_036066
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UniProt
- Q8BGW1
抗原
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