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FTO 抗体 (N-Term)

FTO 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 绵羊, 马, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782980
发货至: 中国
  • 抗原 See all FTO 抗体
    FTO (Fat Mass and Obesity-Associated (FTO))
    抗原表位
    • 17
    • 15
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 61
    • 27
    • 24
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Pig, Cow, 绵羊, 马, 兔, Saccharomyces cerevisiae
    宿主
    • 53
    • 8
    • 1
    • 1
    克隆类型
    • 44
    • 19
    多克隆
    标记
    • 34
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FTO antibody is un-conjugated
    应用范围
    • 56
    • 23
    • 18
    • 14
    • 14
    • 13
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    MKRVQTAEER EREAKKLRLL EELEDTWLPY LTPKDDEFYQ QWQLKYPKLV
    预测反应
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Yeast: 90%
    产品特性
    This is a rabbit polyclonal antibody against Fto. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide corresponding to a region of Mouse
    Top Product
    Discover our top product FTO Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 502 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FTO (Fat Mass and Obesity-Associated (FTO))
    别名
    Fto (FTO 产品)
    别名
    AW743446 antibody, mKIAA1752 antibody, RGD1305121 antibody, FTO, alpha-ketoglutarate dependent dioxygenase antibody, fat mass and obesity associated antibody, fat mass and obesity associated L homeolog antibody, FTO antibody, Fto antibody, fto.L antibody
    背景
    Fto is a dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Fto has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Fto has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Fto has no activity towards 1-methylguanine and no detectable activity towards double-stranded DNA. Fto requires molecular oxygen, alpha-ketoglutarate and iron. Fto contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Fto contributes to the regulation of body size and body fat accumulation.
    Alias Symbols: AW743446, mKIAA1752
    Protein Interaction Partner: Eed,
    Protein Size: 502
    分子量
    58 kDa
    基因ID
    26383
    NCBI登录号
    NM_011936, NP_036066
    UniProt
    Q8BGW1
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