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FTO 抗体 (N-Term)

This anti-FTO antibody is a 兔 多克隆 antibody detecting FTO in WB. Suitable for 人, 小鼠, 大鼠, 犬, 兔, Cow, 绵羊, Pig, 马 和 Saccharomyces cerevisiae.
产品编号 ABIN2782980
发货至: 中国

Quick Overview for FTO 抗体 (N-Term) (ABIN2782980)

抗原

See all FTO 抗体
FTO (Fat Mass and Obesity-Associated (FTO))

适用

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人, 小鼠, 大鼠, 犬, 兔, Cow, 绵羊, Pig, 马, Saccharomyces cerevisiae

宿主

  • 55
  • 8
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克隆类型

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多克隆

标记

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This FTO antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 15
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    N-Term

    序列

    MKRVQTAEER EREAKKLRLL EELEDTWLPY LTPKDDEFYQ QWQLKYPKLV

    预测反应

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Yeast: 90%

    产品特性

    This is a rabbit polyclonal antibody against Fto. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide corresponding to a region of Mouse
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 502 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    FTO (Fat Mass and Obesity-Associated (FTO))

    别名

    Fto

    背景

    Fto is a dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Fto has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Fto has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Fto has no activity towards 1-methylguanine and no detectable activity towards double-stranded DNA. Fto requires molecular oxygen, alpha-ketoglutarate and iron. Fto contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Fto contributes to the regulation of body size and body fat accumulation.
    Alias Symbols: AW743446, mKIAA1752
    Protein Interaction Partner: Eed,
    Protein Size: 502

    分子量

    58 kDa

    基因ID

    26383

    NCBI登录号

    NM_011936, NP_036066

    UniProt

    Q8BGW1
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