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Transglutaminase 2 抗体 (N-Term)

TGM2 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 犬, Pig, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782979
发货至: 中国
  • 抗原 See all Transglutaminase 2 (TGM2) 抗体
    Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
    抗原表位
    • 15
    • 15
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 106
    • 47
    • 37
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 犬, Pig, 马
    宿主
    • 86
    • 34
    • 3
    • 1
    克隆类型
    • 81
    • 43
    多克隆
    标记
    • 65
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Transglutaminase 2 antibody is un-conjugated
    应用范围
    • 90
    • 30
    • 27
    • 26
    • 26
    • 21
    • 19
    • 13
    • 12
    • 11
    • 8
    • 8
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    MAEELVLERC DLELETNGRD HHTADLCREK LVVRRGQPFW LTLHFEGRNY
    预测反应
    Cow: 93%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against TGM2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human TGM2
    Top Product
    Discover our top product TGM2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 687 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Guise, Engel, Williams, Mahdi, Bidwell, Chade: "Biopolymer-delivered vascular endothelial growth factor improves renal outcomes following revascularization." in: American journal of physiology. Renal physiology, Vol. 316, Issue 5, pp. F1016-F1025, (2019) (PubMed).

  • 抗原
    Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
    别名
    TGM2 (TGM2 产品)
    别名
    G-ALPHA-h antibody, GNAH antibody, TG2 antibody, TGC antibody, tgm2 antibody, zgc:101081 antibody, TgaseII antibody, TGM2 antibody, fc12b04 antibody, wu:fc12b04 antibody, zgc:136700 antibody, TGL2 antibody, G[a]h antibody, TGase2 antibody, tTG antibody, tTGas antibody, transglutaminase 2 antibody, transglutaminase 2, C polypeptide A antibody, transglutaminase 2b antibody, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) antibody, transglutaminase 2, C polypeptide antibody, TGM2 antibody, tgm2a antibody, Tgm2 antibody, tgm2b antibody
    背景
    Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, TGM2 is the autoantigen implicated in celiac disease.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: TG2, TGC, GNAH, G-ALPHA-h
    Protein Interaction Partner: UBC, SUMO1, NEDD8, YWHAG, UBE2V1, RPS6KA3, PGD, PAK2, LDHB, G6PD, ECHS1, CSE1L, CKB, ZFYVE19, TXNDC5, SMEK2, UBFD1, CNDP2, YWHAQ, NPEPPS, SLC9A3R1, YWHAZ, FBXO6, ADAR, ABCA1, A2M, VHL, TGM2, SMAD3, SMAD2, HSPA8, HSPA1B, HSPA1A, HP, HNRNPF, GRN, GCGR, FNTA
    Protein Size: 687
    分子量
    77 kDa
    基因ID
    7052
    NCBI登录号
    NM_004613, NP_004604
    UniProt
    P21980
    途径
    Tube Formation, Thromboxane A2 Receptor Signaling
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