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Transglutaminase 2 抗体 (Middle Region)

This anti-Transglutaminase 2 antibody is a 兔 多克隆 antibody detecting Transglutaminase 2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 犬, 马 和 斑马鱼.
产品编号 ABIN2782978
发货至: 中国

Quick Overview for Transglutaminase 2 抗体 (Middle Region) (ABIN2782978)

抗原

See all Transglutaminase 2 (TGM2) 抗体
Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

适用

  • 125
  • 67
  • 48
  • 14
  • 14
  • 7
  • 3
  • 3
  • 3
  • 2
人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 犬, 马, 斑马鱼

宿主

  • 105
  • 51
  • 3
  • 1

克隆类型

  • 100
  • 60
多克隆

标记

  • 87
  • 10
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Transglutaminase 2 antibody is un-conjugated

应用范围

  • 114
  • 51
  • 35
  • 27
  • 27
  • 26
  • 26
  • 24
  • 16
  • 13
  • 12
  • 7
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 15
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    VGRDEREDIT HTYKYPEGSS EEREAFTRAN HLNKLAEKEE TGMAMRIRVG

    预测反应

    Cow: 91%, Dog: 91%, Guinea Pig: 93%, Horse: 91%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

    产品特性

    This is a rabbit polyclonal antibody against TGM2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human TGM2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 548 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

    别名

    TGM2

    背景

    Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, TGM2 is the autoantigen implicated in celiac disease.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: TG2, TGC, GNAH, G-ALPHA-h
    Protein Interaction Partner: UBC, SUMO1, NEDD8, YWHAG, UBE2V1, RPS6KA3, PGD, PAK2, LDHB, G6PD, ECHS1, CSE1L, CKB, ZFYVE19, TXNDC5, SMEK2, UBFD1, CNDP2, YWHAQ, NPEPPS, SLC9A3R1, YWHAZ, FBXO6, ADAR, ABCA1, A2M, VHL, TGM2, SMAD3, SMAD2, HSPA8, HSPA1B, HSPA1A, HP, HNRNPF, GRN, GCGR, FNTA
    Protein Size: 548

    分子量

    62 kDa

    基因ID

    7052

    NCBI登录号

    NM_198951, NP_945189

    途径

    Tube Formation, Thromboxane A2 Receptor Signaling
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