ADCY10 抗体 (N-Term)
(1 reference)Quick Overview for ADCY10 抗体 (N-Term) (ABIN405918)
抗原
See all ADCY10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VGHTVRHEYT VIGQKVNLAA RMMMYYPGIV TCDSVTYNGS NLPAYFFKEL
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against SAC. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SAC
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anti-Adenylate Cyclase 10 (Soluble) (ADCY10) (AA 1101-1200) antibody
ADCY10 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase 10 (Soluble) (ADCY10) (AA 557-583) antibodyADCY10 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22128 unconjugated
anti-Adenylate Cyclase 10 (Soluble) (ADCY10) (AA 396-445) antibodyADCY10 适用: 人, 大鼠, 小鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase 10 (Soluble) (ADCY10) antibodyADCY10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase 10 (Soluble) (ADCY10) (N-Term) antibodyADCY10 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase 10 (Soluble) (ADCY10) (N-Term) antibodyADCY10 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1610 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 22, pp. 7734-44, (2012) (PubMed).
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: "Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 22, pp. 7734-44, (2012) (PubMed).
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- ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))
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别名
- SAC
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背景
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SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HCA2, RP1-313L4.2, SACI, SAC, Sacy
Protein Interaction Partner: PTGIR, SSTR5,
Protein Size: 1610 -
分子量
- 187 kDa
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基因ID
- 55811
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NCBI登录号
- NM_018417, NP_060887
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UniProt
- Q96PN6
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途径
- cAMP Metabolic Process
抗原
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