LAPTM4B 抗体 (Middle Region)
Quick Overview for LAPTM4B 抗体 (Middle Region) (ABIN2782966)
抗原
See all LAPTM4B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- YPNSIQEYIR QLPPNFPYRD DVMSVNPTCL VLIILLFISI ILTFKGYLIS
-
预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
-
产品特性
- This is a rabbit polyclonal antibody against LAPTM4B. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human LAPTM4B
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 317 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- LAPTM4B (Lysosomal Protein Transmembrane 4 beta (LAPTM4B))
-
别名
- LAPTM4B
-
背景
-
LAPTM4B is a multi-pass membrane protein. It belongs to the LAPTM4/LAPTM5 transporter family. LAPTM4b has active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.
Alias Symbols: LAPTM4beta, LC27
Protein Interaction Partner: NAALADL2, TFRC, NEDD4, UBC,
Protein Size: 317 -
分子量
- 35 kDa
-
基因ID
- 55353
-
NCBI登录号
- NM_018407, NP_060877
抗原
-