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KIRREL 抗体 (Middle Region)

This anti-KIRREL antibody is a 兔 多克隆 antibody detecting KIRREL in WB. Suitable for 小鼠, 大鼠, 人, Cow, 犬, 豚鼠, 马 和 兔. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN405910
发货至: 中国

Quick Overview for KIRREL 抗体 (Middle Region) (ABIN405910)

抗原

See all KIRREL (NEPH1) 抗体
KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))

适用

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小鼠, 大鼠, 人, Cow, 犬, 豚鼠, 马, 兔

宿主

  • 22

克隆类型

  • 22
多克隆

标记

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This KIRREL antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    FLEVGTLERY TVERTNSGSG VLSTLTINNV MEADFQTHYN CTAWNSFGPG

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against KIRREL. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human KIRREL
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 757 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ito, Sugihara, Asaka, Toyama, Yoshihara, Furuichi, Wada, Asano: "Glycoprotein hyposialylation gives rise to a nephrotic-like syndrome that is prevented by sialic acid administration in GNE V572L point-mutant mice." in: PLoS ONE, Vol. 7, Issue 1, pp. e29873, (2012) (PubMed).

  • 抗原

    KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))

    别名

    KIRREL

    背景

    KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2, MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-337 AY302131.1 1-337 338-3211 BC109193.1 1-2874 3212-3609 AK001707.1 1904-2301 3610-3628 BC082969.1 2273-2291
    Alias Symbols: FLJ10845, MGC129542, MGC129543, NEPH1
    Protein Interaction Partner: UBC, SAV1, LATS1, GRB2, KIRREL, NPHS2, NPHS1, TJP1,
    Protein Size: 757

    分子量

    84 kDa

    基因ID

    55243

    NCBI登录号

    NM_018240, NP_060710

    UniProt

    Q96J84

    途径

    Regulation of Actin Filament Polymerization
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