Anoctamin 10 抗体 (C-Term)
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北京 101111
Quick Overview for Anoctamin 10 抗体 (C-Term) (ABIN2782940)
抗原
See all Anoctamin 10 (ANO10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- TMEM16K Antibody - C-terminal region
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序列
- LKADIDATLY EQVILEKEMG TYLGTFDDYL ELFLQFGYVS LFSCVYPLAA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against TMEM16K. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TMEM16K
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47389-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Cellular defects by deletion of ANO10 are due to deregulated local calcium signaling." in: Cellular signalling, Vol. 30, pp. 41-49, (2016) (PubMed).
: "Expression of anoctamins in retinal pigment epithelium (RPE)." in: Pflügers Archiv : European journal of physiology, Vol. 468, Issue 11-12, pp. 1921-1929, (2016) (PubMed).
: "A Coding Variant of ANO10, Affecting Volume Regulation of Macrophages, Is Associated with Borrelia Seropositivity." in: Molecular medicine (Cambridge, Mass.), Vol. 21, pp. 26-37, (2015) (PubMed).
: "Anoctamins are a family of Ca2+-activated Cl- channels." in: Journal of cell science, Vol. 125, Issue Pt 21, pp. 4991-8, (2013) (PubMed).
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- Anoctamin 10 (ANO10)
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别名
- TMEM16K
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背景
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Background Information: TMEM16K is a multi-pass membrane protein. It belongs to the anoctamin family. TMEM16K may act as a calcium-activated chloride channel.
Gene Name: Anoctamin 10
Alternative Symbols: SCAR10, TMEM16K
Protein Name: Anoctamin-10
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分子量
- 76kDa
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基因ID
- 55129
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NCBI登录号
- NP_060545
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UniProt
- Q9NW15
抗原
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