CLN6 抗体 (C-Term)
Quick Overview for CLN6 抗体 (C-Term) (ABIN2782927)
抗原
See all CLN6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- RLFLDSNGLF LFSSFALTLL LVALWVAWLW NDPVLRKKYP GVIYVPEPWA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against CLN6. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CLN6
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anti-Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6) (Internal Region) antibody
CLN6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6) (AA 1-43) antibodyCLN6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6) (C-Term) antibodyCLN6 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 兔, 绵羊, 斑马鱼, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6) (AA 108-157) antibodyCLN6 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, Bat, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6) (C-Term) antibodyCLN6 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6) (AA 221-270) antibodyCLN6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 311 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))
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别名
- CLN6
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背景
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CLN6 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely CLN6 involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
Alias Symbols: FLJ20561, HsT18960, nclf, CLN4A
Protein Interaction Partner: RNF2, BMI1, ILK, env, DERL1, VCP, UBC,
Protein Size: 311 -
分子量
- 36 kDa
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基因ID
- 54982
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NCBI登录号
- NM_017882, NP_060352
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UniProt
- Q9NWW5
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途径
- Glycosaminoglycan Metabolic Process
抗原
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