NAGPA 抗体 (N-Term)
This anti-NAGPA antibody is a 兔 多克隆 antibody detecting NAGPA in WB. Suitable for 人, Cow, 犬, 豚鼠, 马, 小鼠, 大鼠 和 斑马鱼.
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Quick Overview for NAGPA 抗体 (N-Term) (ABIN2782884)
抗原
See all NAGPA 抗体
NAGPA
(N-Acetylglucosamine-1-phosphodiester alpha-N-Acetylglucosaminidase (NAGPA))
适用
人, Cow, 犬, 豚鼠, 马, 小鼠, 大鼠, 斑马鱼
宿主
兔
克隆类型
多克隆
标记
This NAGPA antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- N-Term
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序列
- GECLGNVVSD ERRVSSSGGL QNAQFGIRRD GTLVTGYLSE EEVLDTENPF
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against NAGPA. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human NAGPA
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anti-N-Acetylglucosamine-1-phosphodiester alpha-N-Acetylglucosaminidase (NAGPA) (AA 327-438) antibody
NAGPA 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Acetylglucosamine-1-phosphodiester alpha-N-Acetylglucosaminidase (NAGPA) (AA 309-408) antibodyNAGPA 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NAGPA (N-Acetylglucosamine-1-phosphodiester alpha-N-Acetylglucosaminidase (NAGPA))
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别名
- NAGPA
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背景
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Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. This reaction most likely occurs in the trans-Golgi network. This enzyme functions as a homotetramer of two disulfide-linked homodimers. In addition to having an N-terminal signal peptide, the protein's C-terminus contains multiple signals for trafficking it between lysosomes, the plasma membrane, and trans-Golgi network.
Alias Symbols: APAA, UCE
Protein Interaction Partner: ZHX2, DEGS1, NAGPA, EPS15, AP2A1, FURIN,
Protein Size: 515 -
分子量
- 53 kDa
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基因ID
- 51172
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NCBI登录号
- NM_016256, NP_057340
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UniProt
- Q9UK23
抗原
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