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COQ2 抗体 (Middle Region)

This anti-COQ2 antibody is a 兔 多克隆 antibody detecting COQ2 in WB. Suitable for 人, 小鼠, 大鼠, Pig, 犬, 山羊, 马, 兔, Saccharomyces cerevisiae 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2782857
发货至: 中国

Quick Overview for COQ2 抗体 (Middle Region) (ABIN2782857)

抗原

See all COQ2 抗体
COQ2 (Coenzyme Q2 Homolog, Prenyltransferase (COQ2))

适用

人, 小鼠, 大鼠, Pig, 犬, 山羊, 马, 兔, Saccharomyces cerevisiae, 斑马鱼

宿主

  • 3
  • 2

克隆类型

  • 3
  • 2
多克隆

标记

  • 5
This COQ2 antibody is un-conjugated

应用范围

  • 4
  • 3
Western Blotting (WB)
  • 抗原表位

    • 1
    • 1
    • 1
    Middle Region

    序列

    FSGVMWTLIY DTIYAHQDKR DDVLIGLKST ALRFGENTKP WLSGFSVAML

    预测反应

    Dog: 93%, Goat: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 93%, Rat: 86%, Yeast: 91%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against COQ2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human COQ2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 384 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sasaki, Kotoh, Watadani, Matsumoto: "New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 26, Issue 11-12, pp. 619-29, (2015) (PubMed).

  • 抗原

    COQ2 (Coenzyme Q2 Homolog, Prenyltransferase (COQ2))

    别名

    COQ2

    背景

    COQ2 catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. COQ2 mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB.CoQ (ubiquinone) serves as a redox carrier in the mitochondrial respiratory chain and is a lipid-soluble antioxidant. COQ2, or parahydroxybenzoate-polyprenyltransferase (EC 2.5.1.39), catalyzes one of the final reactions in the biosynthesis of CoQ, the prenylation of parahydroxybenzoate with an all-trans polyprenyl group (Forsgren et al., 2004 [PubMed 15153069]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-90 BC020728.1 1-90 91-96 BG699931.1 80-85 97-789 BC020728.1 97-789 790-792 BQ363759.1 169-171 793-1535 BC020728.1 793-1535 1536-1554 BC008804.2 1496-1514
    Alias Symbols: CL640, FLJ26072
    Protein Interaction Partner: UBC,
    Protein Size: 384

    分子量

    42 kDa

    基因ID

    27235

    NCBI登录号

    NM_015697, NP_056512

    UniProt

    Q96H96
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