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Seladin 1 抗体 (N-Term)

DHCR24 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782831
发货至: 中国
  • 抗原 See all Seladin 1 (DHCR24) 抗体
    Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
    抗原表位
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 32
    • 24
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马
    宿主
    • 30
    • 2
    克隆类型
    • 32
    多克隆
    标记
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Seladin 1 antibody is un-conjugated
    应用范围
    • 31
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    FLLPLSLIFD IYYYVRAWVV FKLSSAPRLH EQRVRDIQKQ VREWKEQGSK
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against DHCR24. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human DHCR24
    Top Product
    Discover our top product DHCR24 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 516 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
    别名
    DHCR24 (DHCR24 产品)
    别名
    MGC82737 antibody, zgc:101638 antibody, DCE antibody, Nbla03646 antibody, SELADIN1 antibody, seladin-1 antibody, 2310076D10Rik antibody, 5830417J06Rik antibody, mKIAA0018 antibody, 24-dehydrocholesterol reductase antibody, 24-dehydrocholesterol reductase S homeolog antibody, delta(24)-sterol reductase antibody, DHCR24 antibody, dhcr24.S antibody, dhcr24 antibody, LOC5575872 antibody, CpipJ_CPIJ000670 antibody, Dhcr24 antibody
    背景
    DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: KIAA0018, Nbla03646, SELADIN1, seladin-1, DCE
    Protein Interaction Partner: UBC, env, UBL4A, TP53, MDM2,
    Protein Size: 516
    分子量
    58 kDa
    基因ID
    1718
    NCBI登录号
    NM_014762, NP_055577
    UniProt
    Q15392
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