Seladin 1 抗体 (N-Term)
Quick Overview for Seladin 1 抗体 (N-Term) (ABIN2782831)
抗原
See all Seladin 1 (DHCR24) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- FLLPLSLIFD IYYYVRAWVV FKLSSAPRLH EQRVRDIQKQ VREWKEQGSK
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against DHCR24. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DHCR24
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anti-24-Dehydrocholesterol Reductase (DHCR24) antibody
DHCR24 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 227-516) antibodyDHCR24 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 1-516) antibodyDHCR24 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 1-516) antibodyDHCR24 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (N-Term) antibodyDHCR24 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) antibodyDHCR24 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 38-87) antibodyDHCR24 适用: 人, 小鼠, 大鼠, Cow, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 431-480) antibodyDHCR24 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (N-Term) antibodyDHCR24 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 57-87), (N-Term) antibodyDHCR24 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB17628 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 516 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
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别名
- DHCR24
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背景
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DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: KIAA0018, Nbla03646, SELADIN1, seladin-1, DCE
Protein Interaction Partner: UBC, env, UBL4A, TP53, MDM2,
Protein Size: 516 -
分子量
- 58 kDa
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基因ID
- 1718
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NCBI登录号
- NM_014762, NP_055577
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UniProt
- Q15392
抗原
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