ERVW-1 抗体 (N-Term)
Quick Overview for ERVW-1 抗体 (N-Term) (ABIN2782821)
抗原
See all ERVW-1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- TQTGMSDGGG VQDQAREKHV KEVISQLTRV HGTSSPYKGL DLSKLHETLR
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预测反应
- Human: 100%, Rabbit: 91%
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产品特性
- This is a rabbit polyclonal antibody against ERVWE1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ERVWE1
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anti-Endogenous Retrovirus Group W, Member 1 (ERVW-1) (AA 21-443) antibody
ERVW-1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Endogenous Retrovirus Group W, Member 1 (ERVW-1) antibodyERVW-1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endogenous Retrovirus Group W, Member 1 (ERVW-1) (N-Term) antibodyERVW-1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 538 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))
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别名
- ERVWE1
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背景
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ERVWE1 or syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene.Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The product of this gene, syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Env-W, HERV-7q, HERV-W, HERV-W-ENV, HERVW, env, syncytin, ENV, ENVW, ERVWE1, HERV7Q, HERVWENV
Protein Interaction Partner: SLC1A4, SLC1A5,
Protein Size: 538 -
分子量
- 24 kDa
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基因ID
- 30816
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NCBI登录号
- NM_014590, NP_055405
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UniProt
- Q9UQF0
抗原
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