Myoferlin 抗体 (C-Term)
Quick Overview for Myoferlin 抗体 (C-Term) (ABIN2782797)
抗原
See all Myoferlin (MYOF) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QTEFRIPPRL IIQIWDNDKF SLDDYLGFLE LDLRHTIIPA KSPEKCRLDM
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against FER1L3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human FER1L3
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anti-Myoferlin (MYOF) (AA 655-754) antibody
MYOF 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Myoferlin (MYOF) (AA 700-750) antibodyMYOF 适用: 人, 小鼠, Cow WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myoferlin (MYOF) (AA 1874-1923) antibodyMYOF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Myoferlin (MYOF) (AA 1-190) antibodyMYOF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Myoferlin (MYOF) antibodyMYOF 适用: 人, 小鼠 WB, EIA, IHC (fro) 宿主: 小鼠 Monoclonal 7D2 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 2061 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Myoferlin (MYOF)
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别名
- FER1L3
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背景
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Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. FER1L3 is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length natures have not been determined.
Alias Symbols: FLJ36571, FLJ90777, MYOF, FER1L3
Protein Interaction Partner: UBC, SUMO2, SUMO3, RPA3, RPA2, RPA1, MATR3, ILF2, ATP6V1B1, CDK2, Kdr, Dnm2, ISG15, SUMO1,
Protein Size: 2061 -
分子量
- 235 kDa
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基因ID
- 26509
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NCBI登录号
- NM_013451, NP_038479
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UniProt
- Q9NZM1
抗原
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