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NNT 抗体 (N-Term)

This anti-NNT antibody is a 兔 多克隆 antibody detecting NNT in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 马 和 兔. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2782785
发货至: 中国

Quick Overview for NNT 抗体 (N-Term) (ABIN2782785)

抗原

See all NNT 抗体
NNT (Nicotinamide Nucleotide Transhydrogenase (NNT))

适用

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人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 马, 兔

宿主

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克隆类型

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多克隆

标记

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This NNT antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    IVRGFDTRAA ALEQFKSLGA EPLEVDLKES GEGQGGYAKE MSKEFIEAEM

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against NNT. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human NNT
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1086 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

  • 抗原

    NNT (Nicotinamide Nucleotide Transhydrogenase (NNT))

    别名

    NNT

    背景

    NNT is an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.
    Alias Symbols: MGC126502, MGC126503
    Protein Interaction Partner: MVP, UBC, TIMM10, PTCD1, FKBP8, POFUT1, UQCR11, ATP6V1F, PRPF3, LAMTOR3, SF1, THY1, ABCD3, NDUFS6, NDUFA9, SLC26A2, ATP5B, SLC25A6, SIRT7, MME, HNRNPA1,
    Protein Size: 1086

    分子量

    114 kDa

    基因ID

    23530

    NCBI登录号

    NM_012343, NP_036475

    UniProt

    Q13423

    途径

    Proton Transport
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