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Reticulon 4 抗体 (Middle Region)

This anti-Reticulon 4 antibody is a 兔 多克隆 antibody detecting Reticulon 4 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 马, 豚鼠, Pig 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2782749
发货至: 中国

Quick Overview for Reticulon 4 抗体 (Middle Region) (ABIN2782749)

抗原

See all Reticulon 4 (RTN4) 抗体
Reticulon 4 (RTN4)

适用

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人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 马, 豚鼠, Pig, 斑马鱼

宿主

  • 75
  • 3
  • 3
  • 2
  • 2
  • 2

克隆类型

  • 70
  • 17
多克隆

标记

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  • 1
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This Reticulon 4 antibody is un-conjugated

应用范围

  • 68
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  • 12
  • 6
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  • 2
  • 1
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Western Blotting (WB)
  • 抗原表位

    • 16
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    • 4
    • 4
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    FRIYKGVIQA IQKSDEGHPF RAYLESEVAI SEELVQKYSN SALGHVNCTI

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against RTN4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human RTN4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 392 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Beetz, Koch, Khundadze, Zimmer, Nietzsche, Hertel, Huebner, Mumtaz, Schweizer, Dirren, Karle, Irintchev, Alvarez, Redies, Westermann, Kurth, Deufel, Kessels, Qualmann, Hübner: "A spastic paraplegia mouse model reveals REEP1-dependent ER shaping." in: The Journal of clinical investigation, Vol. 123, Issue 10, pp. 4273-82, (2013) (PubMed).

  • 抗原

    Reticulon 4 (RTN4)

    别名

    RTN4

    背景

    RTN4 belongs to the family of reticulons. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. RTN4 is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates.This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.
    Alias Symbols: ASY, NI220/250, NOGO, NOGO-A, NOGOC, NSP, NSP-CL, Nbla00271, Nbla10545, Nogo-B, Nogo-C, RTN-X, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C
    Protein Interaction Partner: HUWE1, SYT16, ZFYVE21, RTN4, SNX15, ARL6IP1, SNX1, UBC, RPA3, RPA2, RPA1, vpu, BAIAP2, LAMA4, ATF2, CLN8, TMEM65, S100A16, EPPK1, SNX12, ACAA2, SLC9A3R2, TJP1, HNRNPM, ILF3, IGFBP7, DDB1, SLC25A10, CIRBP, TERF1, POT1, RPS27, NR4A1, HLA-DPB1, RTN3, RTN4IP1
    Protein Size: 392

    分子量

    42 kDa

    基因ID

    57142

    NCBI登录号

    NM_207520, NP_997403

    UniProt

    Q9NQC3

    途径

    Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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