EBP 抗体 (N-Term)
Quick Overview for EBP 抗体 (N-Term) (ABIN2782722)
抗原
See all EBP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- LVIEGWFVLY YEDLLGDQAF LSQLWKEYAK GDSRYILGDN FTVCMETITA
-
预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 93%, Rat: 85%
-
产品特性
- This is a rabbit polyclonal antibody against EBP. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EBP
-
-
anti-Emopamil Binding Protein (Sterol Isomerase) (EBP) (AA 2-230) antibody
EBP 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Emopamil Binding Protein (Sterol Isomerase) (EBP) (AA 201-230), (C-Term) antibodyEBP 适用: 人 WB 宿主: 兔 Polyclonal RB41564 unconjugated
anti-Emopamil Binding Protein (Sterol Isomerase) (EBP) (AA 1-30), (N-Term) antibodyEBP 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23728 unconjugated
anti-Emopamil Binding Protein (Sterol Isomerase) (EBP) (AA 77-126) antibodyEBP 适用: 人, 小鼠, 大鼠, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Emopamil Binding Protein (Sterol Isomerase) (EBP) (AA 50-150) antibodyEBP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 230 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))
-
别名
- EBP
-
背景
-
EBP is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in EBP gene cause Chondrodysplasia punctata 2 (CDPX2, also known as Conradi-Hunermann syndrome).Emopamil-binding protein (EBP) is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. EBP shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of EBP is its high content of aromatic amino acid residues (>23 % ) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2, also known as Conradi-Hunermann syndrome).
Alias Symbols: CDPX2, CHO2, CPX, CPXD
Protein Interaction Partner: UBC, MITF, VKORC1, APP, ELAVL1, ESRRG, EBPL,
Protein Size: 230 -
分子量
- 26 kDa
-
基因ID
- 10682
-
NCBI登录号
- NM_006579, NP_006570
-
UniProt
- Q15125
抗原
-
