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HYOU1 抗体 (Middle Region)

HYOU1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782712
发货至: 中国
  • 抗原 See all HYOU1 抗体
    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
    抗原表位
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow
    宿主
    • 41
    • 30
    克隆类型
    • 37
    • 35
    多克隆
    标记
    • 25
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HYOU1 antibody is un-conjugated
    应用范围
    • 62
    • 27
    • 24
    • 14
    • 13
    • 13
    • 12
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    DREVQYLLNK AKFTKPRPRP KDKNGTRAEP PLNASASDQG EKVIPPAGQT
    预测反应
    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against HYOU1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human HYOU1
    Top Product
    Discover our top product HYOU1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 999 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Du, Rong, Hui, Peng, Jin, Li, Wang, Li: "Expression and function of HSP110 family in mouse testis after vasectomy." in: Asian journal of andrology, Vol. 19, Issue 3, pp. 355-361, (2016) (PubMed).

  • 抗原
    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
    别名
    HYOU1 (HYOU1 产品)
    别名
    GRP-170 antibody, Grp170 antibody, HSP12A antibody, ORP-150 antibody, ORP150 antibody, AI415631 antibody, CBP-140 antibody, Cab140 antibody, Orp150 antibody, id:ibd5056 antibody, wu:fd14c05 antibody, zgc:56019 antibody, HYOU1 antibody, orp150 antibody, GRP170 antibody, hypoxia up-regulated 1 antibody, hypoxia up-regulated protein 1 antibody, hypoxia up-regulated 1 S homeolog antibody, HYOU1 antibody, Hyou1 antibody, hyou1 antibody, LOC100380749 antibody, hyou1.S antibody
    背景
    The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal.
    Alias Symbols: DKFZp686N08236, ORP150, Grp170, HSP12A
    Protein Interaction Partner: CLU, HSPA8, UBC, MDM2, RNF2, EZH2, KIF13A, ARMCX3, GANAB, BCAR1, ATP6V1F, XRCC5, MCM7, MCM2, MSH6, XRCC6, ATP6V1B2, BIN1, UBD, env, OS9, NUP37, POLR1C, FBXO6, CDK2, SIRT7, SARM1, H2AFX, IKBKE, EXT2,
    Protein Size: 999
    分子量
    108 kDa
    基因ID
    10525
    NCBI登录号
    NM_006389, NP_006380
    UniProt
    Q9Y4L1
    途径
    ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
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