DDOST 抗体 (N-Term)
Quick Overview for DDOST 抗体 (N-Term) (ABIN310826)
抗原
See all DDOST 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SPSVEDFGGN INVETISAFI DGGGSVLVAA SSDIGDPLRE LGSECGIEFD
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against DDOST. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DDOST
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 456 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))
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别名
- DDOST
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背景
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DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
Alias Symbols: AGE-R1, KIAA0115, MGC2191, OK/SW-cl.45, OST, OST48, WBP1, AGER1, OKSWcl45
Protein Interaction Partner: HUWE1, VAPB, UBC, FAF1, STAU1, ASB11, TRIM13, SUZ12, EED, CLN3, NXT1, SRSF11, FN1, ATF2, STT3B, MAGT1, ZMPSTE24, VDAC2, SSR4, SSR3, SLC25A3, ILF2, KRTCAP2, FBXO6, UBD, AMFR, AUP1, TMEM173, UNC93B1, MAPK6, HDAC5, AGO3, BRCC3, GSTK1, TMBIM4, PGRMC1, SAP18,
Protein Size: 456 -
分子量
- 46 kDa
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基因ID
- 1650
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NCBI登录号
- NM_005216, NP_005207
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UniProt
- Q5VWA5
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途径
- Cell RedoxHomeostasis
抗原
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