FXYD1 抗体 (N-Term)
Quick Overview for FXYD1 抗体 (N-Term) (ABIN2782662)
抗原
See all FXYD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ASLGHILVFC VGLLTMAKAE SPKEHDPFTY DYQSLQIGGL VIAGILFILG
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 79%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against FXYD1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FXYD1
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anti-FXYD Domain Containing Ion Transport Regulator 1 (FXYD1) antibody
FXYD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 1 (FXYD1) (AA 21-92) antibodyFXYD1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 1 (FXYD1) (AA 21-57), (N-Term) antibodyFXYD1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB0857 unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 1 (FXYD1) (AA 69-101), (C-Term) antibodyFXYD1 适用: 大鼠 WB 宿主: 兔 Polyclonal RB49520 unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 1 (FXYD1) (AA 1-92) antibodyFXYD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 92 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))
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别名
- FXYD1
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背景
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FXYD1 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature.This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature.
Alias Symbols: MGC44983, PLM
Protein Interaction Partner: PPP1CA, PPAP2A, DMPK, PRKACA, ATP1B1, ATP1A1, YWHAQ,
Protein Size: 92 -
分子量
- 10 kDa
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基因ID
- 5348
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NCBI登录号
- NM_005031, NP_005022
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UniProt
- O00168
抗原
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