LARGE1 (Middle Region) 抗体
Our Local Distributor
北京 101111
Quick Overview for LARGE1 (Middle Region) 抗体 (ABIN2782650)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
原理
- LARGE1 Antibody - middle region
-
序列
- AHIMELDVQE YEFIVLPNAY MIHMPHAPSF DITKFRSNKQ YRICLKTLKE
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
-
产品特性
- This is a rabbit polyclonal antibody against LARGE. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human LARGE
-
-
anti-LARGE1 (AA 35-142) antibody
适用: 人 WB, FACS 宿主: 小鼠 Monoclonal LARGE-02 unconjugated
anti-LARGE1 (AA 35-142) antibody (PE)适用: 人 ICFC 宿主: 小鼠 Monoclonal LARGE-02 PE
anti-LARGE1 (AA 35-142) antibody (PE)适用: 人 WB, FACS 宿主: 小鼠 Monoclonal PE
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46489-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- LARGE1
-
背景
-
Background Information: This gene encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. The protein encoded by this gene is the glycotransferase that adds the final xylose and glucuronic acid to alpha-dystroglycan and thereby allows alpha-dystroglycan to bind ligands including laminin 211 and neurexin. Mutations in this gene cause several forms of congenital muscular dystrophy characterized by cognitive disability and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in multiple transcript variants that encode the same protein.
Gene Name: LARGE xylosyl- and glucuronyltransferase 1
Alternative Symbols: LARGE, MDC1D, MDDGA6, MDDGB6
Protein Name: LARGE xylosyl- and glucuronyltransferase 1
-
分子量
- 88kDa
-
基因ID
- 9215
-
NCBI登录号
- NP_004728
-
UniProt
- O95461
抗原
-
