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COX15 抗体 (N-Term)

This anti-COX15 antibody is a 兔 多克隆 antibody detecting COX15 in IHC 和 WB. Suitable for 人, 大鼠, 小鼠, 犬, 兔, 斑马鱼, Cow, 豚鼠, 马 和 Saccharomyces cerevisiae. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2782632
发货至: 中国

Quick Overview for COX15 抗体 (N-Term) (ABIN2782632)

抗原

See all COX15 抗体
COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))

适用

人, 大鼠, 小鼠, 犬, 兔, 斑马鱼, Cow, 豚鼠, 马, Saccharomyces cerevisiae

宿主

  • 24
  • 2

克隆类型

  • 25
  • 1
多克隆

标记

  • 16
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This COX15 antibody is un-conjugated

应用范围

  • 13
  • 12
  • 11
  • 4
  • 3
  • 1
Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    DWHLIKEMKP PTSQEEWEAE FQRYQQFPEF KILNHDMTLT EFKFIWYMEY

    预测反应

    Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Yeast: 82%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against COX15. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human COX15
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 388 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Swenson, Cannon, Harris, Taylor, Fox, Khalimonchuk: "Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes." in: The Journal of biological chemistry, Vol. 291, Issue 19, pp. 10411-25, (2016) (PubMed).

  • 抗原

    COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))

    别名

    COX15

    背景

    Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane.Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates several transcript variants diverging in the 3' region including alternate poly A sites. In total, 2 different isoforms are encoded by these variants.
    Alias Symbols: -
    Protein Interaction Partner: UBC, CLN3, MRPS14, NDUFA12, TOMM7, MRPL15, LAMTOR3, SURF1, NDUFS8, NDUFS6, NDUFS4, NDUFA9, CYC1,
    Protein Size: 388

    分子量

    44 kDa

    基因ID

    1355

    NCBI登录号

    NM_004376, NP_004367
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